Browsing by Author "Ozbilum, Nil"
Now showing items 1-7 of 7
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Association between MMP-3 and MMP-9 polymorphisms and coronary artery disease
Beton, Osman; Arslan, Serdal; Acar, Burak; Ozbilum, Nil; Berkan, Ocal (SPANDIDOS PUBL LTD, 2016)Matrix metalloproteinase (MMP)-3 and MMP-9 polymorphisms are characterized by plaque stability in coronary arteries. The aim of the current study was to investigate the 5A/6A polymorphism in the MMP-3 gene and C/T polymorphism ... -
Association between NF-kappa BI and NF-kappa BIA polymorphisms and coronary artery disease
Arslan, Serdal; Korkmaz, Ozge; Ozbilum, Nil; Berkan, Ocal (SPANDIDOS PUBL LTD, 2015)Coronary artery disease (CAD) is the leading cause of fatalities worldwide. Nuclear factor (NF)-kappa B is a transcription factor that controls cell proliferation, differentiation and immunity. To the best of our knowledge, ... -
Effect of TLR10 (2322A/G, 720A/C, and 992T/A) polymorphisms on the pathogenesis of Crimean Congo hemorrhagic fever disease
Kizildag, Sibel; Arslan, Serdal; Ozbilum, Nil; Engin, Aynur; Bakir, Mehmet (WILEY, 2018)Crimean Congo hemorrhagic fever (CCHF) is a tick-borne disease caused by the Crimean Congo hemorrhagic fever virus (CCHFV). Toll-like receptors (TLRs) are type 1 transmembrane proteins of immune cells that play a critical ... -
Is There Any Relationship Between Toll-Like Receptor 3 c.1377C/T and-7C/A Polymorphisms and Susceptibility to Crimean Congo Hemorrhagic Fever?
Engin, Aynur; Arslan, Serdal; Ozbilum, Nil; Bakir, Mehmet (WILEY-BLACKWELL, 2016)Crimean-Congo hemorrhagic fever (CCHF) is an infectious disease that is caused by CCHF virus. A family of transmembrane receptors called as Toll-like receptors (TLRs) selectively acts in recognizing a wide range of microbial ... -
Long non-coding RNAs in the atherosclerotic plaque
Arslan, Serdal; Berkan, Ocal; Lalem, Torkia; Ozbilum, Nil; Goksel, Sabahattin; Korkmaz, Ozge; Cetin, Nilgun; Devaux, Yvan (ELSEVIER IRELAND LTD, 2017)Background and aims: Genetic and environmental factors are important components of the development of atherosclerosis. Long non-coding RNA (lncRNAs) have emerged as regulators of multiple pathophysiological pathways in the ... -
The Role of NF-kappa B1A Promoter Polymorphisms on Coronary Artery Disease Risk
Ozbilum, Nil; Arslan, Serdal; Berkan, Ocal; Yanartas, Mehmed; Aydemir, Eylem Itir (WILEY-BLACKWELL, 2013)Coronary artery disease (CAD), which is now regarded as a chronic inflammatory disease, is the leading cause of death worldwide. Nuclear factor (NF)-B is a transcription factor that plays an important role in the regulation ... -
Toll-like Receptor 7 Gln11Leu, c.4-151A/G, and+1817G/T Polymorphisms in Crimean Congo Hemorrhagic Fever
Arslan, Serdal; Engin, Aynur; Ozbilum, Nil; Bakir, Mehmet (WILEY, 2015)Crimean-Congo hemorrhagic fever (CCHF) is a viral zoonosis. Toll-like receptors (TLRs) initiate signaling cascades leading to the activation of the innate immune system following CCHF infection. In this study, TLR7 (Gln11Leu, ...